The book *I Am Legend*, by American novelist Richard Matheson, is one of the most important works of horror and science fiction, originally published in 1954 and adapted into three films. This classic, which influenced the work of great horror masters such as Stephen King and George A. Romero, has received a special hardcover edition with extras: an interview with Matheson discussing the novel's influences and film adaptations, and a critique by Professor Mathias Classen of Aarhus University, Denmark, analyzing the biocultural aspects of the novel. Matheson's work – from one of the leading authors of the 20th century – has changed the way horror films and books are made today. The use of science, such as medicine and biology, to explain the origins of vampires, as employed in *I Am Legend*, offers the audience a more realistic and plausible perspective, unlike genre greats like H.P. Lovecraft, whose work is rooted in the supernatural. Its influence is so great that, even though the work only mentions vampires, it shaped the imagery of what a zombie apocalypse would be like. The story takes place in the not-too-distant future, when the entire world is ravaged by a merciless plague. Men, women, and even children are transformed into carnivorous monsters, and it is in this post-apocalyptic scenario, overrun by bloodthirsty creatures of the night, that Robert Neville becomes the last man on Earth, spending his days searching for food and supplies, fighting to stay alive and sane. But the infected lurk in the shadows, ready to destroy the last bastion of humanity.